Recombinant Full Length Human CACNG1 Protein, His-Tagged

• Cat.No.: RFL30582HF

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-222 aa
• Description: Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs).
• Molecular Mass: 31 kDa
• AA Sequence: MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAAFILLFLGGLALLLFSLPRMPRNPWESCMDAEPEH
• Purity: > 85% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Lyophilized from PBS, 0.05% Brij-78, 6% Trehalose, pH 7.4. The volume before lyophilization is 57 μL/vial.
• Concentration: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20/-80 centigrade. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Gene Information

• Gene Name: CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 [ Homo sapiens (human) ]
• Official Symbol: CACNG1
• Synonyms: CACNG1; calcium voltage-gated channel auxiliary subunit gamma 1; CACNLG; voltage-dependent calcium channel gamma-1 subunit; L-type calcium channel gamma polypeptide; calcium channel, voltage-dependent, gamma subunit 1; dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma; neuronal dihydropyridine-sensitive calcium channel gamma subunit
• Gene ID: 786
• mRNA Refseq: NM_000727
• Protein Refseq: NP_000718
• MIM: 114209
• UniProt ID: Q06432