Recombinant Full Length Human UBR7 Protein, C-Flag-tagged

• Cat.No.: UBR7-608HFL
• Product Overview: Recombinant Full Length Human UBR7 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 47.8 kDa
• AA Sequence: MAGAEGAAGRQSELEPVVSLVDVLE EDEELENEACAVLGGSDSEKCSYSQ GSVKRQALYACSTCTPEGEE PAGICLACSYECHGSHKLFELYTKR NFRCDCGNSKFKNLECKLLPDKAKV NSGNKYNDNFFGLYCICKRP YPDPEDEIPDEMIQCVVCEDWFHGR HLGAIPPESGDFQEMVCQACMKRCS FLWAYAAQLAVTKISTEDDG LVRNIDGIGDQEVIKPENGEHQDST LKEDVPEQGKDDVREVKVEQNSEPC AGSSSESDLQTVFKNESLNA ESKSGCKLQELKAKQLIKKDTATYW PLNWRSKLCTCQDCMKMYGDLDVLF LTDEYDTVLAYENKGKIAQA TDRSDPLMDTLSSMNRVQQVELICE YNDLKTELKDYLKRFADEGTVVKRE DIQQFFEEFQSKKRRRVDGM
  QYYCSTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: UBR7 ubiquitin protein ligase E3 component n-recognin 7 [ Homo sapiens (human) ]
• Official Symbol: UBR7
• Synonyms: LICAS; C14orf130
• Gene ID: 55148
• mRNA Refseq: NM_175748.4
• Protein Refseq: NP_786924.2
• MIM: 613816
• UniProt ID: Q8N806