Recombinant Full Length Human RPS6 Protein, GST-tagged

• Cat.No.: RPS6-445HF
• Product Overview: Recombinant full length Human RPS6(1 a.a. - 249 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ.

Specification

• Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 53.13 kDa
• Protein length: 249 amino acids
• AA Sequence: MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADA LGEEWKGYVV RISGGNDKQG FPMKQGVLTH GRVRLLLSKG HSCYRPRRTG ERKRKSVRGC IVDANLSVLN LVIVKKGEKD IPGLTDTTVP RRLGPKRASR IRKLFNLSKE DDVRQYVVRK PLNKEGKKPR TKAPKIQRLV TPRVLQHKRR RIALKKQRTK KNKEEAAEYA KLLAKRMKEA KEKRQEQIAK RRRLSSLRAS TSKSESSQK
• Purity: Proprietary Purification
• Applications: ELISA; WB-Re; AP; Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: RPS6 ribosomal protein S6 [ Homo sapiens ]
• Official Symbol: RPS6
• Synonyms: RPS6; ribosomal protein S6; 40S ribosomal protein S6; phosphoprotein NP33; S6
• Gene ID: 6194
• mRNA Refseq: NM_001010
• Protein Refseq: NP_001001
• MIM: 180460
• UniProt ID: P62753