Recombinant Full Length Human PVALB, His-tagged

• Cat.No.: PVALB-2871H
• Product Overview: Recombinant human PVALB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-110 a.a.
• Description: Parvalbumin alpha, also known PVALB, belongs to a larger group of EF hand proteins. It is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. Parvalbumin is expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus.
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSMTDL LNAEDIKKAV GAFSATDSFD HKKFFQMVGLKKKSADDVKK VFHMLDKDKS GFIEEDELGF ILKGFSPDAR DLSAKETKML MAAGDKDGDG KIGVDEFSTL VAES.
• Purity: > 95% by SDS – PAGE.
• MW: 14.6 kDa (134aa) confirmed by MALDI-TOF.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl, 0.1mM PMSF.
• Concentration: 1mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PVALB parvalbumin [ Homo sapiens ]
• Synonyms: PVALB; parvalbumin; OTTHUMP00000197806; OTTHUMP00000197807; OTTHUMP00000197808; parvalbumin alpha
• Gene ID: 5816
• mRNA Refseq: NM_002854
• Protein Refseq: NP_002845
• MIM: 168890
• UniProt ID: P20472
• Chromosome Location: 22q12-q13.1; 22q13
• Function: calcium ion binding