Recombinant Full Length Human NR4A1 Protein

• Cat.No.: NR4A1-348HF
• Product Overview: Recombinant full length Human NUR77 with N terminal proprietary tag; Predicted MWt 91.89 kDa.

Specification

• Description: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 91.890kDa inclusive of tags
• Protein length: 598 amino acids
• AA Sequence: MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASP EAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSS ASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPV DEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGH FSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSP SLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHL EGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYG VRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQ FCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDA GDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLE SAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFG DWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQE PRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLP ELRTLCTRGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: NR4A1 nuclear receptor subfamily 4, group A, member 1 [ Homo sapiens ]
• Official Symbol: NR4A1
• Synonyms: NR4A1; nuclear receptor subfamily 4, group A, member 1; GFRP1, HMR; nuclear receptor subfamily 4 group A member 1; N10; NAK 1; NGFIB; NUR77; TR3
• Gene ID: 3164
• mRNA Refseq: NM_001202233
• Protein Refseq: NP_001189162
• MIM: 139139
• UniProt ID: P22736