Recombinant Full Length Human LRRFIP2 Protein, GST-tagged

• Cat.No.: LRRFIP2-6075HF
• Product Overview: Human LRRFIP2 full-length ORF ( NP_060194.1, 1 a.a. - 400 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 400 amino acids
• Description: The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017]
• Molecular Mass: 71.8 kDa
• AA Sequence: MGTPASGRKRTPVKDRFSAEDEALSNIAREAEARLAAKRAARAEARDIRMRELERQQKELDEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMEELKEGLRQRDELIEKHGLVIIPDGTPNGDVSHEPVAGAITVVSQEAAQVLESAGEGPLDVRLRKLAGEKEELLSQIRKLKLQLEEERQKCSRNDGTVGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDITTLEQSISRLEGQVLRYKTAAENAEKVEDELKAEKRKLQRELRTALDKIEEMEMTNSHLAKRLEKMKANRTALLAQQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 [ Homo sapiens ]
• Official Symbol: LRRFIP2
• Synonyms: LRRFIP2; leucine rich repeat (in FLII) interacting protein 2; leucine-rich repeat flightless-interacting protein 2; HUFI 2; LRR FLII-interacting protein 2; HUFI-2; FLJ20248; FLJ22683; FLJ58304; DKFZp434H2035
• Gene ID: 9209
• mRNA Refseq: NM_001134369
• Protein Refseq: NP_001127841
• MIM: 614043
• UniProt ID: Q9Y608