Recombinant Full Length Human IFNAR1 Protein

• Cat.No.: IFNAR1-250HF
• Product Overview: Recombinant full length Human IFNAR1 with an N terminal proprietary tag; Predicted MWt 87.34 kDa.

Specification

• Description: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 87.340kDa inclusive of tags
• Protein length: 557 amino acids
• AA Sequence: MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDI IDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQ NITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSF TPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDG LSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCL KVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQ NQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQI PDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSE EIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTP VIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLT VYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLI VGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDE YFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQT DEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: IFNAR1 interferon (alpha, beta and omega) receptor 1 [ Homo sapiens ]
• Official Symbol: IFNAR1
• Synonyms: IFNAR1; interferon (alpha, beta and omega) receptor 1; IFNAR; interferon alpha/beta receptor 1; IFRC
• Gene ID: 3454
• mRNA Refseq: NM_000629
• Protein Refseq: NP_000620
• MIM: 107450
• UniProt ID: P17181