Recombinant Full Length Human HNRNPF Protein

• Cat.No.: HNRNPF-236HF
• Product Overview: Recombinant full length Human hnRNP F with N terminal proprietary tag; Predicted MWt 71.72 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 415 amino acids
• Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Form: Liquid
• Molecular Mass: 71.720kDa inclusive of tags
• AA Sequence: MMLGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGA AGVHFIYTREGRQSGEAFVELGSEDDVKMALKKDRESMGH RYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPF GCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFA SQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLK FMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYSTGY GGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSE FTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIE IGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELF LNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGC YGAGYSGQNSMGGYD
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: HNRNPF heterogeneous nuclear ribonucleoprotein F [ Homo sapiens ]
• Official Symbol: HNRNPF
• Synonyms: HNRNPF; heterogeneous nuclear ribonucleoprotein F; HNRPF
• Gene ID: 3185
• mRNA Refseq: NM_001098204
• Protein Refseq: NP_001091674
• MIM: 601037
• UniProt ID: P52597