Recombinant Full Length Human GJB1 Protein, GST-tagged

• Cat.No.: GJB1-5293HF
• Product Overview: Human GJB1 full-length ORF ( NP_000157.1, 1 a.a. - 283 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 58.4 kDa
• Protein length: 283 amino acids
• AA Sequence: MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GJB1 gap junction protein, beta 1, 32kDa [ Homo sapiens ]
• Official Symbol: GJB1
• Synonyms: GJB1; gap junction protein, beta 1, 32kDa; CMTX, CMTX1, gap junction protein, beta 1, 32kD (connexin 32, Charcot Marie Tooth neuropathy, X linked), gap junction protein, beta 1, 32kDa (connexin 32), gap junction protein, beta 1, 32kDa (connexin 32, Charcot Marie Tooth neuropathy, X linked); gap junction beta-1 protein; Charcot Marie Tooth neuropathy; X linked; connexin 32; CX32; connexin-32; GAP junction 28 kDa liver protein; CMTX; CMTX1
• Gene ID: 2705
• mRNA Refseq: NM_000166
• Protein Refseq: NP_000157
• MIM: 304040
• UniProt ID: P08034