Recombinant Full Length Human FYB1 Protein, C-Flag-tagged

• Cat.No.: FYB1-1860HFL
• Product Overview: Recombinant Full Length Human FYB1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 90.4 kDa
• AA Sequence: MAKYNTGGNPTEDVSVNSRPFRVTG PNSSSGIQARKNLFNNQGNASPPAG PSNVPKFGSPKPPVAVKPSS EEKPDKEPKPPFLKPTGAGQRFGTP ASLTTRDPEAKVGFLKPVGPKPINL PKEDSKPTFPWPPGNKPSLH SVNQDHDLKPLGPKSGPTPPTSENE QKQAFPKLTGVKGKFMSASQDLEPK PLFPKPAFGQKPPLSTENSH EDESPMKNVSSSKGSPAPLGVRSKS GPLKPAREDSENKDHAGEISSLPFP GVVLKPAASRGGPGLSKNGE EKKEDRKIDAAKNTFQSKINQEELA SGTPPARFPKAPSKLTVGGPWGQSQ EKEKGDKNSATPKQKPLPPL FTLGPPPPKPNRPPNVDLTKFHKTS SGNSTSKGQTSYSTTSLPPPPPSHP ASQPPLPASHPSQPPVPSLP PRNIKPPFDLKSPVNEDNQDGVTHS DGAGNLDEEQDSEGETYEDIEASKE REKKREKEEKKRLELEKKEQ KEKEKKEQEIKKKFKLTGPIQVIHL AKACCDVKGGKNELSFKQGEQIEII RITDNPEGKWLGRTARGSYG YIKTTAVEIDYDSLKLKKDSLGAPS RPIEDDQEVYDDVAEQDDISSHSQS GSGGIFPPPPDDDIYDGIEE EDADDGSTLQVQEKSNTWSWGILKM LKGKDDRKKSIREKPKVSDSDNNEG SSFPAPPKQLDMGDEVYDDV DTSDFPVSSAEMSQGTNFGKAKTEE KDLKKLKKQEKEEKDFRKKFKYDGE IRVLYSTKVTTSITSKKWGT RDLQVKPGESLEVIQTTDDTKVLCR NEEGKYGYVLRSYLADNDGEIYDDI ADGCIYDND TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: FYB1 FYN binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: FYB1
• Synonyms: FYB; ADAP; THC3; PRO0823; SLAP130; SLAP-130
• Gene ID: 2533
• mRNA Refseq: NM_001465.6
• Protein Refseq: NP_001456.3
• MIM: 602731
• UniProt ID: O15117