Recombinant Full Length Human F2RL1 Protein

• Cat.No.: F2RL1-4496HF
• Product Overview: Human F2RL1 full-length ORF (AAH12453.1) recombinant protein without tag.

Specification

• Description: This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 44.1 kDa
• Protein length: 573 amino acids
• AA Sequence: MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH 8.0 containing 2% glycerol.

Gene Information

• Gene Name: F2RL1 coagulation factor II (thrombin) receptor-like 1 [ Homo sapiens ]
• Official Symbol: F2RL1
• Synonyms: PAR2; GPR11; F2RL1; coagulation factor II (thrombin) receptor-like 1
• Gene ID: 2150
• mRNA Refseq: NM_005242
• Protein Refseq: NP_005233
• MIM: 600933
• UniProt ID: P55085