Recombinant Full Length Human ELAVL3 Protein, C-Flag-tagged

• Cat.No.: ELAVL3-2154HFL
• Product Overview: Recombinant Full Length Human ELAVL3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 39.4 kDa
• AA Sequence: MVTQILGAMESQVGGGPAGPALPNG PLLGTNGATDDSKTNLIVNYLPQNM TQDEFKSLFGSIGDIESCKL VRDKITGQSLGYGFVNYSDPNDADK AINTLNGLKLQTKTIKVSYARPSSA SIRDANLYVSGLPKTMSQKE MEQLFSQYGRIITSRILVDQVTGVS RGVGFIRFDKRIEAEEAIKGLNGQK PLGAAEPITVKFANNPSQKT GQALLTHLYQSSARRYAGPLHHQTQ RFRLDNLLNMAYGVKSPLSLIARFS PIAIDGMSGLAGVGLSGGAA GAGWCIFVYNLSPEADESVLWQLFG PFGAVTNVKVIRDFTTNKCKGFGFV TMTNYDEAAMAIASLNGYRL GERVLQVSFKTSKQHKA TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: ELAVL3 ELAV like RNA binding protein 3 [ Homo sapiens (human) ]
• Official Symbol: ELAVL3
• Synonyms: HUC; HUCL; PLE21
• Gene ID: 1995
• mRNA Refseq: NM_001420.4
• Protein Refseq: NP_001411.2
• MIM: 603458
• UniProt ID: Q14576