Recombinant Full Length Human DOC2A Protein, GST-tagged

• Cat.No.: DOC2A-4064HF
• Product Overview: Human DOC2A full-length ORF ( AAH63436, 1 a.a. - 400 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 69.74 kDa
• Protein length: 400 amino acids
• AA Sequence: MRGRRGDRMTINIQEHMAINVCPGP IRPIRQISDYFPRGPGPEGGGGSGG EAPAHLVPLALAPPAALLGATTPED GAEVDSYDSDDATALGTLEFDLLYD RASCTLHCSILRAKGLKPMDFNGLA DPYVKLHLLPGACKANKLKTKTQRN TLNPVWNEDLTYSGITDDDITHKVL RIAVCDEDKLSHNEFIGEIRVPLRR LKPSQKKHFNICLERQVPLASPSSM SAALRGISCYLKELEQAEQGQGLLE ERGRILLSLSYSSRRRGLLVGILRC AHLAAMDVNGYSDPYVKTYLRPDVD KKSKHKTCVKKKTLNPEFNEEFFYE IELSTLATKTLEVTVWDYDIGKSND FIGGVSLGPGARGEARKHWSDCLQQ PDAALERWHTLTSELPPAAGALSSA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DOC2A double C2-like domains, alpha [ Homo sapiens ]
• Official Symbol: DOC2A
• Synonyms: DOC2A; double C2-like domains, alpha; double C2-like domain-containing protein alpha; doc2-alpha; Doc2
• Gene ID: 8448
• mRNA Refseq: NM_003586
• Protein Refseq: NP_003577
• MIM: 604567
• UniProt ID: Q14183