Recombinant Full Length Human DMRT1 Protein

• Cat.No.: DMRT1-128HF
• Product Overview: Recombinant full length Human DMRT1 with N terminal proprietary tag; Predicted MWt 67.14 kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 373 amino acids
• Description: This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
• Form: Liquid
• Molecular Mass: 67.140kDa inclusive of tags
• AA Sequence: MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGKASGALVG AASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCR NHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVA LRRQQAQEEELGISHPIPLPSAAELLVKRENNGSNPCLMT ECSGTSQPPPASVPTTAASEGRMVIQDIPAVTSRGHVENT PDLVSDSTYYSSFYQPSLFPYYNNLYNCPQYSMALAADSA SGEVGNPLGGSPVKNSLRGLPGPYVPGQTGNQWQMKNMEN RHAMSSQYRMHSYYPPPSYLGQSVPQFFTFEDAPSYPEAR ASVFSPPSSQDSGLVSLSSSSPISNKSTKAVLECEPASEP SSFTVTPVIEEDE
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: DMRT1 doublesex and mab-3 related transcription factor 1 [ Homo sapiens ]
• Official Symbol: DMRT1
• Synonyms: DMRT1; doublesex and mab-3 related transcription factor 1; doublesex- and mab-3-related transcription factor 1; DM domain expressed in testis 1; DMT1
• Gene ID: 1761
• mRNA Refseq: NM_021951
• Protein Refseq: NP_068770
• MIM: 602424
• UniProt ID: Q9Y5R6