Recombinant Full Length Human CRNKL1 Protein, GST-tagged

• Cat.No.: CRNKL1-2087HF
• Product Overview: Human CRNKL1 full-length ORF ( NP_057736.4, 1 a.a. - 848 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 119.68 kDa
• Protein length: 848 amino acids
• AA Sequence: MTATVENLTFQKDTLGNAVDKNTSRLELRSYSLAGRHGSTEPLVLAWSSQFRRLTWGCALDALHRSPCVAASQHGVTHLIRSSRTPHSTRCRKEDAQPGHHGNGAASVTAQARGQRSVLQVPLPVPRSCLFSESFVVSVSSQSRFLASVPGTGVQRSTAADMAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQFELSSGKEGSLTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTDDGSDAGWEEYFDYIFPEDAANQPNLKLLAMAKLWKKQQQEKEDAEHHPDEDVDESES
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CRNKL1 crooked neck pre-mRNA splicing factor 1 [ Homo sapiens (human) ]
• Official Symbol: CRNKL1
• Synonyms: CRNKL1; crooked neck pre-mRNA splicing factor 1; Crooked Neck Pre-MRNA Splicing Factor 1; SYF3 Pre-MRNA-Splicing Factor; Crooked Neck Homolog; HCRN; CRN; Crooked Neck Pre-MRNA Splicing Factor-Like 1 (Drosophila); Crooked Neck (Drosophila Crn Homolog)-Like 1; Crooked Neck Pre-MRNA Splicing Factor-Like 1; Crn, Crooked Neck-Like 1 (Drosophila); Crooked Neck-Like Protein 1; Crn, Crooked Neck-Like 1; Crooked Neck-Like 1; MSTP021; Clf1; SYF3; CLF; crooked neck-like protein 1; Crn, crooked neck-like 1; SYF3 pre-mRNA-splicing factor; crooked neck homolog; crooked neck pre-mRNA splicing factor-like 1; crooked neck-like 1
• Gene ID: 51340
• mRNA Refseq: NM_001278625
• Protein Refseq: NP_001265554
• MIM: 610952
• UniProt ID: Q9BZJ0