Recombinant Full Length Human CD86 Protein

• Cat.No.: CD86-68HF
• Product Overview: Recombinant full length Human CD86 with proprietary tag, 62.26kDa inclusive of tag.

Specification

• Description: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 62.260kDa inclusive of tags
• Protein length: 329 amino acids
• AA Sequence: MDPQCTMGLSNILFVMAFLLSGAAPLKIQAYFNETADLPC QFANSQNQSLSELVVFWQDQENLVLNEVYLGKEKFDSV HSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCIIHHKKPT GMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLT CSSIHGYPEPKKMSVLLRTKNSTIEYDGIMQKSQDNVTEL YDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPFSI ELEDPQPPPDHIPWITAVLPTVIICVMVFCLILWKWKKKK RPRNSYKCGTNTMEREESEQTKKREKIHIPERSDETQR VFKSSKTSSCDKSDTCF
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: CD86 CD86 molecule [ Homo sapiens ]
• Official Symbol: CD86
• Synonyms: CD86; CD86 molecule; CD28LG2, CD86 antigen (CD28 antigen ligand 2, B7 2 antigen); T-lymphocyte activation antigen CD86; B lymphocyte antigen B7 2; B7 2; B7.2
• Gene ID: 942
• mRNA Refseq: NM_001206924
• Protein Refseq: NP_001193853
• MIM: 601020
• UniProt ID: P42081