Recombinant Full Length Human ATG16L1 Protein, GST-tagged

• Cat.No.: ATG16L1-1215HF
• Product Overview: Human ATG16L1 full-length ORF ( NP_110430.4, 1 a.a. - 523 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 523 amino acids
• Description: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
• Molecular Mass: 84.7 kDa
• AA Sequence: MAQLRIKHQE ELTELHKKRG ELAQLVIDLN NQMQRKDREM QMNEAKIAEC LQTISDLETE CLDLRTKLCD LERANQTLKD EYDALQITFT ALEGKLRKTT EENQELVTRW MAEKAQEANR LNAENEKDSR RRQARLQKEL AEAAKEPLPV EQDDDIEVIV DETSDHTEET SPVRAISRAA TKRLSQPAGG LLDSITNIFG RRSVSSFPVP QDNVDTHPGS GKEVRVPATA LCVFDAHDGE VNAVQFSPGS RLLATGGMDR RVKLWEVFGE KCEFKGSLSG SNAGITSIEF DSAGSYLLAA SNDFASRIWT VDDYRLRHTL TGHSGKVLSA KFLLDNARIV SGSHDRTLKL WDLRSKVCIK TVFAGSSCND IVCTEQCVMS GHFDKKIRFW DIRSESIVRE MELLGKITAL DLNPERTELL SCSRDDLLKV IDLRTNAIKQ TFSAPGFKCG SDWTRVVFSP DGSYVAAGSA EGSLYIWSVL TGKVEKVLSK QHSSSINAVA WSPSGSHVVS VDKGCKAVLW AQY
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ATG16L1 ATG16 autophagy related 16-like 1 (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: ATG16L1
• Synonyms: ATG16L1; ATG16 autophagy related 16-like 1 (S. cerevisiae); APG16 autophagy 16 like (S. cerevisiae) , APG16L, ATG16 autophagy related 16 like (S. cerevisiae) , ATG16L; autophagy-related protein 16-1; ATG16A; FLJ10035; WDR30; APG16L beta; WD repeat domain 30; IBD10; APG16L; ATG16L; FLJ00045; FLJ10828; FLJ22677
• Gene ID: 55054
• mRNA Refseq: NM_001190266
• Protein Refseq: NP_001177195
• MIM: 610767
• UniProt ID: Q676U5