Recombinant Equine IL-12 p40

• Cat.No.: IL12B-100E
• Product Overview: Equine IL-12/IL-23 p40 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.

Specification

• Species: Equine
• Source: Yeast
• Tag: Non
• Description: IL-12 is a member of the IL-12 family, which includes IL-12, IL-23, IL-27, and IL-35. Like other IL-12 family members, IL-12 is a heterodimeric cytokine. IL-12 is encoded by two separate genes, IL-12A (p35) and IL-12B (p40). The active heterodimer, and a homodimer of p40 are formed following protein synthesis. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-gamma and TNF-alpha from T and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-gamma.
• Form: Lyophilized
• Molecular Mass: 34.9 kDa
• AA Sequence: IWELEKDVYV VELDWYPDAP GEMVVLTCNT PEEEGITWTS AQSNEVLGSG KTLTIQVKEF GDAGWYTCHK GGEVLSHSHL LLHKKEDGIW STDILKDQKE SKNKTFLKCE AKNYSGRFTC WWLTAISTDL KFSVKSSRGS SDPRGVTCGA ATLSAERVSV DDREYKKYTV ECLEGSACPA AEESLPIEIV VDAVHKLKYE NYTSGFFIRD IIKPDPPKNL QLKPLKNSRQ VEVSWEYPET WSTPHSYFSL TFSIQVQGKN KKERKDRLFM DETSATVTCH KDGQIRVQAR DRYYSSSWSE WASVSCS (307)
• Applications: The Equine IL-12/IL-23 p40 protein can be used in cell culture, as an IL-12/IL-23 p40 ELISA Standard, and as a Western Blot Control.
• Storage: -20 C