Recombinant Cynomolgus monkey CD3D Protein, His-tagged

• Cat.No.: CD3D-136C
• Product Overview: Recombinant Cynomolgus monkey CD3D protein with His tag was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
• Source: HEK293
• Species: Cynomolgus monkey
• Tag: His
• Form: Lyophilized
• Molecular Mass: 14.3 kDa
• Protein length: 171
• AA Sequence: MEHSTFLSGLVLATLLSQVSPFKIPVEELEDRVFVKCNTSVTWVEGTVGTLLTNNTRLDLGKRILDPRGIYRCNGTDIYKDKESAVQVHYRMCQNCVELDPATLAGIIVTDVIATLLLALGVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSRLGGNWARNK
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: CD3D CD3d molecule, delta (CD3-TCR complex) [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: CD3D
• Synonyms: CD3D; CD3d molecule, delta (CD3-TCR complex); T-cell surface glycoprotein CD3 delta chain
• Gene ID: 699582
• mRNA Refseq: XM_015115818
• Protein Refseq: XP_014971304
• UniProt ID: Q95LI8