Recombinant Cynomolgus Monkey CCL2 Protein

• Cat.No.: CCL2-01C
• Product Overview: Cynomolgus Monkey CCL2 (MCP-1) was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.

Specification

• Species: Cynomolgus
• Source: Yeast
• Description: Chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemotactic protein-1 (MCP-1), is a small cytokine belonging to the CC chemokine family. There are at least 27 distinct members of the C-C subgroup reported for mammals. They are characterized by two adjacent cysteines. CCL2 (MCP-1) recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. CCL2 (MCP-1) is implicated in pathogeneses of several diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis.
• Form: Lyophilized without carrier protein.
• Molecular Mass: 8.7 kDa
• AA Sequence: QPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQIQTPKP
• Unit Definition: >95% as visualized by SDS-PAGE analysis.
• Applications: The Cynomolgus Monkey CCL2 (MCP-1) endotoxin-free recombinant protein can be used in cell culture, as an ELISA Standard, and as a Western Blot Control.
• Storage: Stable for up to twelve months from date of receipt at -20 centigrade. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20 centigrade. Avoid repeated freeze/thaw cycles.
• Reconstitution: Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.

Gene Information

• Gene Name: CCL2 C-C motif chemokine ligand 2 [ Macaca fascicularis (crab-eating macaque) ]
• Official Symbol: CCL2
• Synonyms: CCL2; C-C motif chemokine ligand 2; MCP1; MCP-1; SCYA2; C-C motif chemokine 2; Monocyte chemoattractant protein 1; Monocyte chemotactic protein 1; Small-inducible cytokine A2; monocyte chemoattractant protein-1
• Gene ID: 102135739
• mRNA Refseq: NM_001284872
• Protein Refseq: NP_001271801
• MIM: P61274