Recombinant Cynomolgus CD3D protein, His-tagged
Cat.No. : | CD3D-1183C |
Product Overview : | Recombinant Cynomolgus CD3D (Phe22-Ala105) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
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Species : | Cynomolgus |
Source : | HEK293 |
Tag : | His |
Protein Length : | Phe22-Ala105 |
Description : | CD3D is also known as CD3-DELTA, T3D, and is a single-pass type I membrane protein. CD3D is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. Defects in CD3D cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T-/B+/NK+ SCID) which is a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. |
Predicted N Terminal : | Phe22 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 14.3 kDa. The protein migrates as 26-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name | CD3D |
Official Symbol | CD3D |
Synonyms | CD3D; CD3d molecule, delta (CD3-TCR complex); CD3d antigen, delta polypeptide (TiT3 complex) , T3D; T-cell surface glycoprotein CD3 delta chain; CD3 delta; OKT3, delta chain; CD3 antigen, delta subunit; T-cell receptor T3 delta chain; CD3d antigen, delta polypeptide (TiT3 complex); T3D; CD3-DELTA |
Gene ID | 102133701 |
mRNA Refseq | NM_001287688.1 |
Protein Refseq | NP_001274617.1 |
UniProt ID | Q95LI8 |
◆ Recombinant Proteins | ||
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CD3D-5284H | Recombinant Human CD3D Protein (Met1-Ala105), C-Fc tagged | +Inquiry |
RFL34411OF | Recombinant Full Length Sheep T-Cell Surface Glycoprotein Cd3 Delta Chain(Cd3D) Protein, His-Tagged | +Inquiry |
CD3D-0799H | Recombinant Human CD3D Protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
CD3D-1274HCL | Recombinant Human CD3D cell lysate | +Inquiry |
CD3D-1466CCL | Recombinant Cynomolgus CD3D cell lysate | +Inquiry |
CD3D-1381MCL | Recombinant Mouse CD3D cell lysate | +Inquiry |
Not For Human Consumption!
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