Recombinant COVID-19 Spike protein, Fc-tagged

• Cat.No.: Spike-416V
• Product Overview: 2019-nCoV Spike S is expressed from mammalian with a Fc tag at the C-terminal. It contains Val16-Glu1188.

Specification

• Species: COVID-19
• Source: HEK293
• Tag: Fc
• Protein Length: Val16-Glu1188
• Description: The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensinconverting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 158.3 kDa. Due to glycosylation, the protein migrates to 230- 250KDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 1EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: S
• Official Symbol: S
• Synonyms: S protein, Spike glycoprotein, S glycoprotein, COVID-19
• Gene ID: 43740568
• Protein Refseq: YP_009724390.1
• UniProt ID: P0DTC2