Recombinant Bovine Vascular Endothelial Growth Factor A

• Cat.No.: VEGFA-366B
• Product Overview: Recombinant Bovine VEGF-A was expressed inYeast.MW= 19.2 kDa (164 aa).

Specification

• Species: Bovine
• Source: Yeast
• Tag: Non
• Description: Vascular endothelial growth factor (VEGF), a potent proangiogenic cytokine is the key signal used by oxygen-hungry cells to promote growth of blood vessels. It binds to specialized receptors on the surfaces of endothelial cells and directs them to build new vessels. VEGF are crucial regulators of vascular development during embryogenesis (vasculogenesis) and blood-vessel formation in the adult (angiogenesis). Abnormal VEGF function is associated with inflammatory diseases including atherosclerosis, and hyperthyroidism.
• Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
• Purification: Ion-exchange chromatography.
• Purity: >95% as visualized by SDS-PAGE analysis.
• Amino Acid Sequence: APMAEGGQKP HEVVKFMDVY QRSFCRPIET LVDIFQEYPD EIEFIFKPSC VPLMRCGGCC NDESLECVPT EEFNITMQIM RIKPHQSQHI GEMSFLQHNK CECRPKKDKA RQENPCGPCS ERRKHLFVQD PQTCKCSCKN TDSRCKARQL ELNERTCRCD KPRR.
• Bioactivity: In testing.
• Stability And Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: VEGFA vascular endothelial growth factor A [ Bos taurus ]
• Synonyms: vascular endothelial growth factor A; VEGFA; VEGF; VPF; VEGF-A; vascular permeability factor
• Gene ID: 281572
• mRNA Refseq: NM_174216.1
• Protein Refseq: NP_776641.1
• UniProt ID: P15691
• Chromosome Location: 23
• Pathway: Bladder cancer; Cytokine-cytokine receptor interaction; Focal adhesion; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; mTOR signaling pathway
• Function: cytokine activity; growth factor activity; heparin binding; protein homodimerization activity