Recombinant Bovine transforming growth factor beta 3 Protein, His tagged
Cat.No. : | TGFB3-32B |
Product Overview : | DNA sequence encoding Bovine TGFB3 sp (A6QP91, 341-452aa) including a C terminal His tag was expressed in HEK293 cells. |
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Species : | Bovine |
Source : | HEK293 |
Tag : | His |
Protein Length : | 341-452aa |
Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. |
Tag : | C-His |
Bio-activity : | The ED(50) was determined by the ability to inhibit the proliferation of mouse HT-2 cells 0.05-0.1 ng/mL, corresponding to a specific activity of 2×10^7 units/mg. |
Molecular Mass : | 13-15 kDa |
Endotoxin : | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg). |
Purity : | > 95%, as determined by SDS-PAGE and HPLC |
Usage : | This product is for research purposes only. It may not be used for therapeutics or diagnostic purposes. |
Storage : | The lyophilized protein is stable for at least 2 years from date of receipt at -20 centigrade. |
Storage Buffer : | Lyophilized from 0.2 μm filtered PBS solution pH7.4 |
Reconstitution : | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
Gene Name | TGFB3 transforming growth factor beta 3 [ Bos taurus (cattle) ] |
Official Symbol | TGFB3 |
Synonyms | TGFB3; transforming growth factor beta 3; transforming growth factor beta-3 proprotein |
Gene ID | 538957 |
mRNA Refseq | NM_001101183 |
Protein Refseq | NP_001094653 |
UniProt ID | A6QP91 |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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