Recombinant 2019-nCoV N protein

• Cat.No.: N-127V
• Product Overview: Recombinant 2019-nCoV N protein was expressed in E. coli and purified by Ni column.

Specification

• Description: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
• Source: E. coli
• Species: 2019-nCov
• Form: Liquid. PBS, pH 8.0.
• Molecular Mass: 47.08 kDa
• Storage: For short term storage, store at 4 centigrade. For long term storage, store at -20~-70 centigrade, avoiding freeze/thaw cycles.
• Concentration: 1.0 mg/ml
• Publications:
  Biomaterials and Oxygen Join Forces to Shape the Immune Response and Boost COVID-19 Vaccines (2021)

Gene Information

• Gene Name: N
• Official Symbol: N
• Synonyms: GU280_gp10
• Gene ID: 43740575
• Protein Refseq: YP_009724397.2