Native Rat Coagulation Factor II

Cat. No. :	F2-5286R
Description :	F2is proteolytically cleaved to form thrombin in the first step of thecoagulation cascade, which ultimately results in the stemming of blood loss.F2 in turn acts as a serine protease that converts soluble fibrinogen intoinsoluble strands of fibrin, as well as catalyzing many othercoagulation-related reactions.
Source :	Rat plasma
Form :	Liquid in 50%Glycero.
Purity :	> 95% by SDS-PAGEanalysis.
MolecularWeight :	72,000
Concentration :	5.0mg/ml
Storage :	Store at -20°C.
Pathways :	BloodClotting Cascade; Cell surface interactions at the vascular wall; ClassA/1(Rhodopsin-like receptors); Common Pathway; Complement and CoaqulationCascades; Diabetes pathways; FOXA2 and FOXA3 transcription factor networks; ExtrinsicPathway; Formation of Fibrin Clot (Clotting Cascade); Hemostasis; IntrinsicPathway; Regulation of actin cytoskeleton; Selenium Pathway; SignalTransduction
Tag :	Non

Gene Name	F2coagulation factor II [ Rattus norvegicus]
Official Symbol	F2
Synonyms	F2; coagulation factor II; prothrombin; thrombin; coagulationfactor2; EC 3.4.21.5
Gene ID	29251
mRNA Refseq	NM_022924
Protein Refseq	NP_075213
Chromosome Location	3q24
Function	peptidase activity; serine-typeendopeptidase activity; calcium ion binding; receptor binding; contributes toreceptor binging; thrombospondin receptor activity