Native Rat Coagulation Factor II

• Cat.No.: F2-5286R
• Product Overview: Rat F2 isprepared from fresh frozen rat plasma. Purity is determined by SDS PAGE analysis.

Specification

• Species: Rat
• Source: Rat plasma
• Tag: Non
• Description: F2is proteolytically cleaved to form thrombin in the first step of thecoagulation cascade, which ultimately results in the stemming of blood loss.F2 in turn acts as a serine protease that converts soluble fibrinogen intoinsoluble strands of fibrin, as well as catalyzing many othercoagulation-related reactions.
• Form: Liquid in 50%Glycero.
• Purity: > 95% by SDS-PAGEanalysis.
• MolecularWeight: 72,000
• Concentration: 5.0mg/ml
• Storage: Store at -20°C.
• Pathways: BloodClotting Cascade; Cell surface interactions at the vascular wall; ClassA/1(Rhodopsin-like receptors); Common Pathway; Complement and CoaqulationCascades; Diabetes pathways; FOXA2 and FOXA3 transcription factor networks; ExtrinsicPathway; Formation of Fibrin Clot (Clotting Cascade); Hemostasis; IntrinsicPathway; Regulation of actin cytoskeleton; Selenium Pathway; SignalTransduction

Gene Information

• Gene Name: F2coagulation factor II [ Rattus norvegicus]
• Official Symbol: F2
• Synonyms: F2; coagulation factor II; prothrombin; thrombin; coagulationfactor2; EC 3.4.21.5
• Gene ID: 29251
• mRNA Refseq: NM_022924
• Protein Refseq: NP_075213
• Chromosome Location: 3q24
• Function: peptidase activity; serine-typeendopeptidase activity; calcium ion binding; receptor binding; contributes toreceptor binging; thrombospondin receptor activity