Native Mushroom Agaricus bisporus Lectin (ABA/ABL), Texas Red-Conjugated

• Cat.No.: ABA/ABL-528M
• Product Overview: Native Mushroom Agaricus bisporus Lectin (ABA/ABL) - Texas Red
  Blood Group Specificity: Non-specific
  Preferred Sugar Specificity: Galactoseβ1-3N-Acetylgalactosamine
  Inhibiting or Eluting Sugar: Fetuin
  Divalent Ions: None Required
  Excitation: 595 nm
  Emission: 615 nm
  Mitogenic Activity: No
  Hazardous Shipping: Non-hazardous
  Fluorescence: Red

Specification

• Species: Mushroom
• Source: Mushroom
• Description: Agaricus bisporus agglutinin (ABA) is an affinity-purified tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-β-1,3-N-acetylgalactosamine and another for galactose-β-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins. Texas Red is a red-fluorescent dye and when bound to Agaricus bisporus Lectin (ABA/ABL) can show the binding pattern of this lectin in cellular imaging applications. There is very little overlap between the emission spectra of Texas Red and FITC making this combination ideal for dual-labeling experiments. Rhodamine dyes, such as Texas Red, are more photostable and less sensitive to pH change when compared to other dyes such as fluorescein.
• Form: Liquid
• Purity: High Purity Grade
• Stability: Shelf Life: 1 year
• Storage: At 2-8 centigrade.
• Concentration: 2 mg/mL

Gene Information

• Official Symbol: ABA/ABL
• Synonyms: Agaricus bisporus Lectin; ABA/ABL