Native Mushroom Agaricus bisporus Lectin (ABA/ABL), Ferritin-Conjugated

• Cat.No.: ABA/ABL-252M
• Product Overview: Native Mushroom Agaricus bisporus Lectin (ABA/ABL) - Ferritin
  Blood Group Specificity: Non-specific
  Preferred Sugar Specificity: Galactoseβ1-3N-Acetylgalactosamine
  Inhibiting or Eluting Sugar: Fetuin
  Divalent Ions: None Required
  Mitogenic Activity: No
  Hazardous Shipping: Non-hazardous

Specification

• Species: Mushroom
• Source: Mushroom
• Description: Agaricus bisporus agglutinin (ABA) is an affinity-purified tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-β-1,3-N-acetylgalactosamine and another for galactose-β-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins. Agaricus bisporus Lectin (ABA/ABL) is conjugated to ferritin, that has a molecular weight of 474,000 g/mol (all 24 subunits combined). Ferritin-conjugated ABA/ABL can be used to visualize localization of specific saccharide moieties and examine the distribution of plasma membrane glycoproteins. These conjugates can be viewed via electron microscopy.
• Form: Liquid
• Purity: High Purity Grade
• Stability: Shelf Life: 1 year
• Storage: At 2-8 centigrade.
• Concentration: 1 mg/mL

Gene Information

• Official Symbol: ABA/ABL
• Synonyms: Agaricus bisporus Lectin; ABA/ABL