Native Mushroom Agaricus bisporus Lectin (ABA/ABL), AP-Conjugated

• Cat.No.: ABA/ABL-001M
• Product Overview: Native Mushroom Agaricus bisporus Lectin (ABA/ABL) - AP (Alkaline Phosphatase)
  Blood Group Specificity: Non-specific
  Preferred Sugar Specificity: Galactoseβ1-3N-Acetylgalactosamine
  Inhibiting or Eluting Sugar: Fetuin
  Divalent Ions: None Required
  Mitogenic Activity: No
  Hazardous Shipping: Non-hazardous

Specification

• Species: Mushroom
• Source: Mushroom
• Description: Agaricus bisporus agglutinin (ABA) is an affinity-purified tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-β-1,3-N-acetylgalactosamine and another for galactose-β-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins.
  Alkaline phosphatase (AP) is conjugated to affinity purified Agaricus bisporus Lectin (ABA/ABL) to show the binding of ABA/ABL in many applications including Western blotting and ELISA. Alkaline phosphatase is a large protein (140 kDa) that catalyzes the hydrolysis of phosphate groups from a substrate resulting in a colored or fluorescent product. The optimal enzymatic activity of this protein is between pH 8 and 10, and its reaction rate remains linear, improving sensitivity over time.
• Form: Liquid
• Purity: High Purity Grade
• Stability: Shelf Life: 1 year
• Storage: At 2-8 centigrade.
• Concentration: 1 mg/mL

Gene Information

• Official Symbol: ABA/ABL
• Synonyms: Agaricus bisporus Lectin; ABA/ABL