Native Mouse Mb

• Cat.No.: Mb-160M
• Product Overview: Native Mouse Mb was purified from Mouse Heart.

Specification

• Species: Mouse
• Source: Mouse Heart
• Tag: Non
• Description: Mouse Heart MYOGLOBIN contains a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. Mouse Myoglobin is found in skeletal and cardiac muscle cells and is capable of reversibly binding molecular oxygen and enhancing the rate of oxygen diffusion through the muscle cell. Myoglobin is an oxygen carrier in the cytoplasm and appears to be responsible for the transport of oxygen from the cell membrane to the mitochondrion. Myoglobin (Mb) is a Haem containing protein and implicated as a cause of acute renal failure following damage to muscle tissue (e.g. rhabdomyolysis, severe crush trauma, malignant hyperthermia, status epilepticus and neuroleptic malignant syndrome), due to its toxicity to renal tubular epithelium.
• Form: Liquid in 50% Glycerol, 75 mM NaCl, 5 mM sodium phosphate, 0.05% NaN3
• Molecular Mass: 17 kDa
• Purity: ≥90% by SDS-PAGE
• Storage: -20 °C
• Concentration: >0.2 mg/mL

Gene Information

• Gene Name: Mb myoglobin [ Mus musculus ]
• Official Symbol: Mb
• Synonyms: MB; myoglobin; AI325109
• Gene ID: 17189
• mRNA Refseq: NM_001164047
• Protein Refseq: NP_001157519
• Function: heme binding; iron ion binding; metal ion binding; oxygen binding; oxygen transporter activity