Native Jimson weed Datura stramonium Lectin (DSA/DSL), Texas Red-Conjugated

• Cat.No.: DSA/DSL-536J
• Product Overview: Native Jimson weed Datura stramonium Lectin (DSA/DSL) - Texas Red
  Blood Group Specificity: Non-specific
  Preferred Sugar Specificity: (N-Acetylglucosamine)2-4
  Inhibiting or Eluting Sugar: Chitin Hydrolysate
  Divalent Ions: None Required
  Excitation: 595 nm
  Emission: 615 nm
  Mitogenic Activity: Yes
  Hazardous Shipping: Non-hazardous
  Fluorescence: Red

Specification

• Description: Datura stramonium agglutinin or lectin (DSA/DSL) is purified by affinity chromatography. Seeds of Datura stramonium contain at least three different carbohydrate-binding proteins, and the most prominent lectin is a dimeric glycoprotein composed of two nonidentical subunits that contains 40% carbohydrate. DSL prefers binding to (GlcNAc)2-4 and elutes with the sugar chitin hydrolysate. DSL binds well in the acidic pH range and its affinity decreases above pH 8. 0. This agglutinin has blood group A, B, and O specificity. Studies have shown that DSA can act as a biomarker for neoplastic urotherial cells. Texas Red is a red-fluorescent dye and when bound to Datura stramonium Lectin (DSA/DSL) can show the binding pattern of this lectin in cellular imaging applications. There is very little overlap between the emission spectra of Texas Red and FITC making this combination ideal for dual-labeling experiments. Rhodamine dyes, such as Texas Red, are more photostable and less sensitive to pH change when compared to other dyes such as fluorescein.
• Source: Jimson weed
• Species: Jimson weed
• Form: Liquid
• Purity: High Purity Grade
• Stability: Shelf Life: 1 year
• Storage: At 2-8 centigrade.
• Concentration: 5 mg/mL

Gene Information

• Official Symbol: DSA/DSL
• Synonyms: Datura stramonium Lectin; DSA/DSL