Native Jimson weed Datura stramonium Lectin (DSA/DSL), Ferritin-Conjugated

• Cat.No.: DSA/DSL-259J
• Product Overview: Native Jimson weed Datura stramonium Lectin (DSA/DSL) - Ferritin
  Blood Group Specificity: Non-specific
  Preferred Sugar Specificity: (N-Acetylglucosamine)2-4
  Inhibiting or Eluting Sugar: Chitin Hydrolysate
  Divalent Ions: None Required
  Mitogenic Activity: Yes
  Hazardous Shipping: Non-hazardous

Specification

• Description: Datura stramonium agglutinin or lectin (DSA/DSL) is purified by affinity chromatography. Seeds of Datura stramonium contain at least three different carbohydrate-binding proteins, and the most prominent lectin is a dimeric glycoprotein composed of two nonidentical subunits that contains 40% carbohydrate. DSL prefers binding to (GlcNAc)2-4 and elutes with the sugar chitin hydrolysate. DSL binds well in the acidic pH range and its affinity decreases above pH 8. 0. This agglutinin has blood group A, B, and O specificity. Studies have shown that DSA can act as a biomarker for neoplastic urotherial cells. Datura stramonium Lectin (DSA/DSL) is conjugated to ferritin, that has a molecular weight of 474,000 g/mol (all 24 subunits combined). Ferritin-conjugated lectins can be used to visualize localization of specific saccharide moieties and examine the distribution of plasma membrane glycoproteins. These conjugates can be viewed via electron microscopy.
• Source: Jimson weed
• Species: Jimson weed
• Form: Liquid
• Purity: High Purity Grade
• Stability: Shelf Life: 1 year
• Storage: At 2-8 centigrade.
• Concentration: 1 mg/mL

Gene Information

• Official Symbol: DSA/DSL
• Synonyms: Datura stramonium Lectin; DSA/DSL