Description :	Fractionated Sambucus nigra lectin (EBL I+II, also known as SNA) is is composed of two ricin-related lectins. EBL I+II is a tetrameric glycoprotein with a recognition of the Neu5Ac(?2-6)Gal or GalNAc linkage in glycoconjugates. EBL I is composed of an A-chain with enzymatic activity and a B-chain with carbohydrate-binding activity. EBL II consists only of carbohydrate-binding B-chains. EBL I+II induces caspase-dependent apoptosis at low concentrations (nM) order, leading to typical symptoms of cell death in sensitive cells. This effect seems independent from the catalytic activity of the A-chain, but depends on the carbohydrate binding B-chain.
Source :	Elderberry
Species :	Elderberry
Form :	Powder
Storage :	At -20 centigrade.

Official Symbol	SNA/EBL I+II
Synonyms	Sambucus nigra Lectin; SNA/EBL I+II

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Cat.No. :	SNA/EBL I+II-703E
Product Overview :	Native Elderberry Sambucus nigra Lectin (SNA/EBL I+II) - Semi-Pure Preferred Sugar Specificity: Sialic Acid Inhibiting or Eluting Sugar: Lactose > β-Galactose Divalent Ions: None Required Mitogenic Activity: Yes Hazardous Shipping: Non-hazardous

Native Elderberry Sambucus nigra Lectin (SNA/EBL I+II)