Native Camel's foot tree Bauhinia purpurea Lectin (BPL/BPA), Ferritin-Conjugated

• Cat.No.: BPL/BPA-256C
• Product Overview: Native Camel's foot tree Bauhinia purpurea Lectin (BPL/BPA) - Ferritin
  Blood Group Specificity: Non-specific
  Preferred Sugar Specificity: Galβ3GalNAc
  Inhibiting or Eluting Sugar: Lactose
  Divalent Ions: None Required
  Mitogenic Activity: Yes
  Hazardous Shipping: Non-hazardous

Specification

• Species: Camel's foot tree
• Source: Camel's foot tree
• Description: Bauhinia purpurea agglutinin or lectin (BPA/BPL) is a tetrameric lectin with a molecular weight of 195,000. BPA is lactose-specific and elutes with the sugar lactose. It has specificity for blood groups A, B, O (-SA). Treatment of erythrocytes with neuraminidase or trypsin will increase the agglutination reaction, indicating that the receptor is masked by terminal carbohydrates. Although binding specificity is similar to that of peanut agglutinin, tissue staining patterns of these two lectins are distinct. Makela's group 2 sugars, particularly N-acetyl-D-galactosamine, are potent inhibitors. The native protein appears to be stable in detergent solution. Bauhinia purpurea Lectin (BPL/BPA) is conjugated to ferritin, that has a molecular weight of 474,000 g/mol (all 24 subunits combined). Ferritin-conjugated lectins can be used to visualize localization of specific saccharide moieties and examine the distribution of plasma membrane glycoproteins. These conjugates can be viewed via electron microscopy.
• Form: Liquid
• Stability: Shelf Life: 1 year
• Storage: At 2-8 centigrade.
• Concentration: 1 mg/mL

Gene Information

• Official Symbol: BPL/BPA
• Synonyms: Bauhinia purpurea Lectin; BPL/BPA