MSCA1 Antibody-coupled magnetic MicroBeads

• Cat.No.: MSCA1-391M

Specification

• Species: Human
• Capacity: for 1×10^9 total cells
• Background: The Anti-MSCA-1 (W8B2) MicroBeads recognize the mesenchymal stromal cell antigen-1 (MSCA-1), which is identical to tissue non-specific alkaline phosphatase.
  MSCA-1 was shown to be restricted to MSCs in the CD271bright population in human bone marrow. These CD271brightCD45dim MSCs have a much higher clonogenic capacity compared to the CD271+CD45+ fraction in bone marrow. Therefore, MSCA-1 is a highly specific marker to isolate MSCs with a high proliferative potential from bone marrow. MSCA-1 expression was not found on placenta-derived MSCs after culture.
  Antibodies against MSCA-1 show broad interspecies cross-reactivity, such as dog, pig, sheep, goat and monkey.