Mouse Anti-MAP1LC3A Monoclonal Antibody

• Cat.No.: DMABT-H17746
• Product Overview: Mouse Anti-MAP1LC3A Monoclonal Antibody

Specification

• Antigen Description: Macroautophagy mediates the bulk degradation of cytoplasmic components. These componentsare delivered to lysosomes via autophagosomes. The rat microtubule-associated protein2light chain4(LC3), a homologue of yeast Atg8 (Aut7/Apg8), localizes to autophagosomal membranes after post-translational modifications. The C-terminal fragment of LC3 is cleaved immediately following synthesis to yield a cytosolic form called LC3-I (18 kDa). A subpopulation of LC3-I is further converted to an autophagosome-associating form, LC3-II (16 kDa). This antibody can detect both forms of LC3.
• Target: MAP1LC3A
• Host: Mouse
• Isotype: IgG1 k
• species: Human
• Clone: 5F23
• Conjugation: N/A
• Applications: Flow Cyt,ICC,IHC,WB
• Storage: -20°C
• Size: 200 μg
• Ship: 4°C
• Tag: Non

Gene Information

• Gene Name: MAP1LC3A microtubule-associated protein2light chain4alpha [ Homo sapiens ]
• Official Symbol: MAP1LC3A
• Synonyms: MAP1LC3A; microtubule-associated protein2light chain4alpha; ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3
• Gene ID: 8199
• MIM: 601242
• UniProt ID: Q9H492
• Chromosome Location: 20q11.22