Mouse Anti-Human ADAM Metallopeptidase Domain 12 Monoclonal Antibody
Cat.No. : | CABT-676MH |
Product Overview : | Mouse Anti-Human ADAM metallopeptidase domain 12 Monoclonal Antibody. |
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Species : | Human |
Source : | Mouse |
Tag : | Non |
Antigen Dscription : | This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis. |
Host Animal : | Mouse |
Species Reactivity : | Human |
Immunogen : | A recombinant polypeptide corresponding to amino acids 208-305 of human ADAM12, expressed as a GST fusion protein. |
Clone : | 2H4 |
Isotype : | IgG3 |
Format : | Purified |
Presentation : | Liquid; In PBS, pH 7.2, containing no preservative. |
Applications : | ELISA (this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 μg/well, 100 μl total volume. Variables associated with assay conditions will dictate the proper working dilution); Immunoblotting (1-5 μg/ml). |
Storage : | Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw. |
Officialsymbol : | ADAM12 |
Gene Name | ADAM12 ADAM metallopeptidase domain 12 [ Homo sapiens ] |
Synonyms | ADAM12; ADAM metallopeptidase domain 12; MCMP; MCMPMltna; MLTN; MLTNA; A Disintegrin and Metalloprotease Domain 12 S isoform; ADAM12 precursor (EC 3.4.24); Meltrin alpha; ADAM12 ADAM metallopeptidase domain 12; OTTHUMP00000020727; OTTHUMP00000046766; a disintegrin and metalloproteinase domain 12 (meltrin alpha); EC 3.4.24.; A disintegrin and metalloproteinase domain 12 |
Gene ID | 8038 |
mRNA Refseq | NM_003474 |
Protein Refseq | NP_003465 |
MIM | 602714 |
UniProt ID | O43184 |
Chromosome Location | 10q26.3 |
Pathway | Signaling by EGFR |
Function | SH3 domain binding; metal ion binding ; metalloendopeptidase activity; peptidase activity; protein binding; zinc ion binding |
◆ Recombinant Proteins | ||
ADAM12-274H | Recombinant Human ADAM12 Protein, GST-tagged | +Inquiry |
ADAM12-233H | Active Recombinant Human ADAM12, His-tagged | +Inquiry |
ADAM12-2799M | Recombinant Mouse ADAM12 Protein (206-706 aa), His-Myc-tagged | +Inquiry |
ADAM12-74H | Recombinant Human ADAM12 Protein, His-tagged | +Inquiry |
ADAM12-1277M | Recombinant Mouse ADAM12 Protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
CPBT-676RH | Rabbit Anti-Human ADAM Metallopeptidase Domain 12 Polyclonal Antibody | +Inquiry |
ADAM12-2592HCL | Recombinant Human ADAM12 cell lysate | +Inquiry |
Not For Human Consumption!
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