Mouse Anti-HTLV-1 p40 Monoclonal Antibody

• Cat.No.: CAB311

Specification

• Species: Human
• Source: Mouse
• Tag: Non
• Antigen Information: HTLV-1 is the etiological agent for Adult T-Cell Leukemia which encodes a 40kDa cell-transforming oncoprotein called Tax. HTLV-1 Tax protein sensitizes cells to apoptotic cell death induced by DNA damaging agents. Constitutive Activation of TAK1 by HTLV-1 Tax-dependent Overexpression of TAB2 Induces Activation of JNK-ATF2 but Not IKK-NF-kB.
• Immunogen: r.HTLV TAX protein.
• Ig Subclass: Mouse IgG2a.
• Purification Method: Ion exchange column.
• Protein Concentration: 1mg/ml in PBS (after reconstitution).
• Titer: By direct ELISA (against recombinant gp24), 1:50,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).
• Applications: Direct ELISA, Western Blot, Immunoprecipitation.
• Shipping Conditions: Antibody is shipped lyophilized at ambient temperature.
• Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C.
• Reconstitution: Reconstitute with H2O. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
• Storage: In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Gene Information

• Gene Name: tax p40 [ Human T-lymphotropic virus 1 ]
• Synonyms: Tax; p40
• Gene ID: 1491938
• Protein Refseq: NP_057864