Matrix Metalloproteinase-14 (MMP-14) fluorometric drug discovery Kit

• Cat.No.: Kit-0575
• Product Overview: A QuantiZyme Assay System. The MMP-14 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay sytem designed to screen for inhibitors of matrix metalloproteinase-14 (MMP-14, membrane-type matrix metalloproteinase 1, MT1-MMP) using a quenched fluorogenic peptide: OMNIMMP fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties. The assays are performed in a convenient 96-well microplate format. Also included are active enzyme, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.

Specification

• Size: 96 wells
• Applications: Fluorescence microscopy, HTS
• Storage: -80°C
• Kit Components: MMP-14 enzyme (human) (recombinant), substrate, calibration standard, Assay Buffer, 96-well white microplate.
• Tag: Non