Human Parathyroid Hormone Reference standard

• Cat.No.: PTH-191H

Specification

• Species: Human
• Tag: Non
• Enzyme Unit: By definition, each ampoule contains 0.100 INTERNATIONAL UNITS of hPTH (i.e. 100 MILLI-INTERNATIONAL UNITS).
• Usage: For all practical purposes, each ampoule of the IRP contains the same quantity of the above substances. Dissolve the total contents of the ampoule in a known quantity of a suitable buffer containing 0.2% crystalline albumin, free of protease activity (Caygill, 1977), to minimize the loss of peptide by surface adsorption. No attempt should be made to weigh out any portion of the freeze dried material as it cannot be assumed that the parathyroid hormone is distributed homogeneously in the freeze dried plug. For economy in use, particularly in immunoassay, aliquots of a stock solution may be frozen rapidly in dry ice and stored at -40 °C for several months. The diluent used for preparation of a stock solution and the stability of such aliquots should be carefully assessed within the assay system in which they are to be used.
• Notes: This preparation is not for administration to humans. The preparation contains material of human origin, and either the final product or the source materials, from which it is derived, have been tested and found negative for HBsAg, anti-HIV and HCV RNA. However, as with all preparations of human origin, this material cannot be assumed to be free from infectious agents. The container and its contents should be used and discarded according to your own laboratory procedures. Such procedures probably will include the wearing of protective gloves and avoiding the generation of aerosols. Care should be exercised in opening the container to avoid cuts.
• Storage: Unopened ampoules should be stored at -20°C. Please note: because of the inherent stability of lyophilized material, Creative Biomart may ship these materials at ambient temperature.

Gene Information

• Gene Name: PTH parathyroid hormone [ Homo sapiens ];
• Official Symbol: PTH
• Synonyms: PTH1; parathyroid hormone; parathyrin; prepro-PTH; parathormone; parathyroid hormone 1; preproparathyroid hormone
• Gene ID: 5741
• mRNA Refseq: NM_000315
• Protein Refseq: NP_000306
• MIM: 168450
• UniProt ID: P01270
• Chromosome Location: 11p15.3-p15.1
• Pathway: Class B/2 (Secretin family receptors), organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem
• Function: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; peptide hormone receptor binding; type 1 parathyroid hormone receptor binding