Hamster Anti-CTLA4 Monoclonal Antibody
Cat.No. : | DMABT-H18898 |
Product Overview : | Hamster Anti-CTLA4 Monoclonal Antibody |
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- Gene Information
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Species : | Mouse |
Source : | Hamster |
Tag : | APC |
Antigen Description : | CD152, also known as CTLA-4 or Ly-56, is a44kD member of the immunoglobulin superfamily. It is expressed on activated T and B lymphocytes. CD152 is similar to CD28 in amino acid sequence, structure, and genomic organization and these two receptors share common B7 family counter-receptors (B7-1, B7-2). Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regulates cell-mediated immune responses. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation. |
Target : | CTLA4 |
Immunogen : | Mouse CTLA-4-mouse IgG2a fusion protein |
Isotype : | IgG |
species : | Mouse |
Clone : | VD20-5C0 |
Conjugation : | APC |
Applications : | Flow Cyt |
Preparation : | The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody. |
Usage recommendation : | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤1.0 μg per million cells in 100 μl volume. It is recommended that the reagent be titrated for optimal performance for each application. |
Concentration : | 0.2 mg/ml |
Storage : | The antibody solution should be stored undiluted at 4 °C and protected from prolonged exposure to light.Do not freeze. |
Size : | 25 μg;100 μg |
Gene Name | Ctla4 cytotoxic T-lymphocyte-associated protein 4 [ Mus musculus ] |
Official Symbol | CTLA4 |
Synonyms | CTLA4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte protein 4; CD152 antigen; cytotoxic T-lymphocyte-associated antigen 4; Cd152; Ly-56; Ctla-4; |
Gene ID | 12477 |
mRNA Refseq | NM_009843 |
Protein Refseq | NP_033973 |
Pathway | Adaptive Immune System, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CTLA4 inhibitory signaling, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; |
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◆ Cell & Tissue Lysates | ||
CTLA4-1047CCL | Recombinant Cynomolgus CTLA4 cell lysate | +Inquiry |
CTLA4-2179MCL | Recombinant Mouse CTLA4 cell lysate | +Inquiry |
CTLA4-2526HCL | Recombinant Human CTLA4 cell lysate | +Inquiry |
Not For Human Consumption!
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