DPP4 Activity Fluorometric Assay Kit
Cat.No. : | Kit-0314 |
Product Overview : | Simple procedure; takes ~ 40 minutes Fast and convenient Sensitive , reliable HTS assay |
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Tag : | Non |
Description : | Dipeptidyl peptidase-4 (DPP4), also known as adenosine deaminase complexing protein 2 or CD26 (cluster of differentiation 26) is a protein that, in humans, is encoded by the DPP4 gene. The substrates of CD26/DPP4 are proline (or alanine) containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPP4 plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1 and hence its inhibition by drugs such as Sitagliptin have been used for treatment of diabetes mellitus type 2. DPP4 also appears to work as a suppressor in the development of cancer and tumors. In DPP4 Activity Assay Kit, DPP4 cleaves a substrate to release a quenched fluorescent group, AMC (7-Amino-4-Methyl Coumarin), (Ex/Em = 360/460 nm). This assay is rapid, simple, sensitive, and reliable, as well as, suitable for high throughput activity screening of DPP4. This kit detects DPP4 activity as low as 3 µU per well. |
Applications : | This kit detects DPP4 activity as low as 3 µU per well |
Usage : | For Research Use Only! Not For Use in Humans. |
Storage : | -20°C |
Size : | 100 assays |
Kit Components : | • DPP4 Assay Buffer • DPP4 Substrate (H-Gly-Pro-AMC) • DPP4 Positive Control • AMC Standard (1 mM) • DPP4 Inhibitor (Sitagliptin) |
Target Species : | Mammalian |
Detection method : | Fluorescence (Ex/Em 360/460 nm) |
Compatible Sample Types : | Cell and Tissue culture lysatess, plasma, serum, other biological fluids, cell culture medium etc |
◆ Recombinant Proteins | ||
Dpp4-2369M | Recombinant Mouse Dpp4 protein, His-SUMO-tagged | +Inquiry |
DPP4-8313H | Active Recombinant Human DPP4, His tagged | +Inquiry |
DPP4-783H | Recombinant Human DPP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Dpp4-7874M | Recombinant Mouse Dpp4 protein, His-tagged | +Inquiry |
DPP4-27255TH | Recombinant Human DPP4, His-tagged | +Inquiry |
◆ Native Proteins | ||
DPP4-197H | Native Human Dipeptidyl Peptidase IV | +Inquiry |
DPP4-31H | Active Native Human DPP4 | +Inquiry |
◆ Cell & Tissue Lysates | ||
DPP4-2979HCL | Recombinant Human DPP4 cell lysate | +Inquiry |
DPP4-733CCL | Recombinant Cynomolgus DPP4 cell lysate | +Inquiry |
Not For Human Consumption!
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