Recombinant Mouse CD33 Antigen, Fc-tagged

• Cat.No.: Cd33-6889M
• Product Overview: A DNA sequence encoding the extracellular domain of mouse Cd33 ( Met 1 - Glu 240 ) was fused with the Fc region of human IgG1 at the C-terminus. It comprises 465 amino acids and has a calculated molecular mass of 51.6 kDa.

Specification

• Species: Mouse
• Source: Human Cells
• Tag: Fc
• Protein Length: 465aa
• Description: Mouse myeloid cell surface antigen Cd33 is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Cd33 contains 1 Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain.
• Predicted N Terminal: Gln 17
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
• Molecular Mass: The secreted recombinant mouse Cd33 / Fc is a disulfide-linked homodimer. The reduced monomer comprises 465 amino acids and has a calculated molecular mass of 51.6 kDa. As a result of glycosylation, the apparent molecular mass of rm CD33 / Fc monomer is approximately 55 - 60 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: 1.0 eu/μg of the protein as determined by the lal
• Purity: >90 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70 °C.
• Storage: Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: Cd33 CD33 antigen [ Mus musculus ]
• Official Symbol: Cd33
• Synonyms: CD33; CD33 antigen; myeloid cell surface antigen CD33; sialic acid-binding Ig-like lectin 3; gp67; Siglec-3
• Gene ID: 12489
• mRNA Refseq: NM_001111058
• Protein Refseq: NP_001104528
• Pathway: Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem
• Function: sugar binding