CD62L protein-coupled magnetic MicroBeads

• Cat.No.: CD62L-5032M

Specification

• Species: Mouse
• Capacity: for 2×10^9 total cells
• Background: CD62L is highly expressed on naive T cells and down-regulated upon activation. It is also expressed on a small subset of memory T cells, the central memory T cells, which can be distinguished from naive T cells by their high expression of CD44. Furthermore, CD62L is expressed on most thymocytes, naive cytotoxic T cells, B cells, dendritic cells, macrophages, NK cells, neutrophils, and eosinophils.
  For isolation of CD4+CD62L+ naive T cells, the CD4+CD62L+ T Cell Isolation Kit II is available.
• Application: Naive T cells isolated following a MultiSort strategy were used for studies on cytokine expression, receptor signaling, and T cell activation by different antigen-presenting cells.