Buffy Coat REAlease CD8 protein-coupled magnetic MicroBeads

• Cat.No.: CD8-3291M

Specification

• Species: Human
• Capacity: for 1 buffy coat
• Background: The CD8 antigen forms a complex together with the T cell receptor and acts as an accessory molecule in the recognition of MHC class I/peptide complexes by the TCR heterodimer on CD8+ cytotoxic T cells. The CD8 molecule consists of either an α/β heterodimer or an α/α homodimer. It is expressed strongly on cytotoxic T cells and dimly on a subset of NK cells. CD8 is found on most thymocytes and on about one third of all peripheral blood T cells. CD8+ cytotoxic T cells play an important role in the killing of virus-infected cells and tumor cells.
• Application: The purified CD8+ cells are bead-free, practical for consecutive magnetic isolation and optionally label-free with epitopes available for any downstream application. The isolated cells are suited for further flow cytometric analyses, molecular biology applications, and functional studies.