Buffy Coat CD4/CD8 protein-coupled magnetic MicroBeads

• Cat.No.: CD4/CD8-4932M

Specification

• Species: Human
• Capacity: for 1 buffy coat
• Background: The CD4 antigen is expressed on T helper (Tʜ) cells and at a lower level on monocytes and dendritic cells. The CD4 antigen is an accessory molecule in the recognition of MHC class II/peptide complexes by the TCR heterodimer on CD4+ Tʜ cells. The CD8 antigen is expressed on cytotoxic T cells and on a subset of CD16+ NK cells. The CD8 antigen acts as an accessory molecule in the recognition of MHC class I/peptide complexes by the TCR heterodimer on CD8+ cytotoxic T cells.
• Application: The purified CD4+ and CD8+ cells are well suited for further flow cytometric, functional, or molecular analysis.