Biotinylated Recombinant Human SELE Protein, His-tagged
Cat.No. : | SELE-215H |
Product Overview : | Biotinylated Recombinant Human E-selectin is produced by Human 293 Cells. The target gene encoding W22-P556 is expressed with an 8His tag at the C terminus. |
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Species : | Human |
Source : | HEK293 |
Tag : | His |
Description : | E-Selectin is a kDa cell surface glycoprotein that belongs to the selectin family. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha, E-selectin plays an important role in recruiting leukocytes to the site of injury during inflammation. E-selectin also mediates the adhesion of tumor cells to endothelial cells, through binding to E-selectin ligands expressed by neutrophils, monocytes, eosinophils, memory-effector T-like lymphocytes, natural killer cells or cancer cells. In addition, studies have found that levels of E-Selectin may be elevated in subjects with various pathological conditions. |
Form : | Lyophilized frum a 0.2 um filtered solution of PBS, pH7.2. |
Molecular Mass : | Predicted Molecular Weight: 61.9kDa Apparent Molecular Weight: Biotinylated E-selectin appeared as a smear between 66.2-116kDa in a reducing SDS-PAGE gel due to glycosylation. |
AA Sequence : | W22-P556 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Purity : | >95% |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. |
Reconstitution : | It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Quality Statement : | Purity: greater than 95% as determined by reducing SDS-PAGE. |
Shipping : | The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below. |
Gene Name | SELE selectin E [ Homo sapiens (human) ] |
Official Symbol | SELE |
Synonyms | E-selectin; CD62 antigen-like family member E; Endothelial leukocyte adhesion molecule 1; Leukocyte-endothelial cell adhesion molecule 2; ELAM; ESEL; CD62E; ELAM1; LECAM2; selectin-e |
Gene ID | 6401 |
mRNA Refseq | NM_000450.2 |
Protein Refseq | NP_000441.2 |
MIM | 131210 |
UniProt ID | P16581 |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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