Active Recombinant Rat Met Protein

• Cat.No.: Met-4417R
• Product Overview: Rat Met (X96786, 958 a.a. - end) partial recombinant protein expressed in Sf9 cells.

Specification

• Species: Rat
• Source: Insect Cells
• Tag: Non
• Protein Length: 958-end a.a.
• Description: MET is a single pass tyrosine kinase receptor essential for embryonic development, organogenesis and wound healing. Hepatocyte growth factor/Scatter Factor (HGF/SF) and its splicing isoform (NK1, NK2) are the only known ligands of the MET receptor. MET is normally expressed by cells of epithelial origin, while expression of HGF/SF is restricted to cells of mesenchymal origin. When HGF/SF binds its cognate receptor MET it induces its dimerization through a not yet completely understood mechanism leading to its activation.
• Form: Liquid
• Bio-activity: The specific activity of Met was determined to be 46 nmol/min/mg.
• Molecular Mass: 74.0 kDa
• Purity: >= 90% by SDS-PAGE
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol)

Gene Information

• Gene Name: Met met proto-oncogene [ Rattus norvegicus ]
• Official Symbol: Met
• Synonyms: MET; met proto-oncogene; hepatocyte growth factor receptor; c-Met; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase; Hgfr
• Gene ID: 24553
• mRNA Refseq: NM_031517
• Protein Refseq: NP_113705