Active Recombinant Pig CSF2 Protein (Ala18-Lys144), N-His tagged, Animal-free, Carrier-free

• Cat.No.: CSF2-207P
• Product Overview: Recombinant Pig CSF2 Protein (Ala18-Lys144) with N-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first identified as a Growth Factors due to its ability to induce proliferation and differentiation of bone marrow progenitors into granulocytes and macrophages. GM-CSF is produced by multiple cell types including activated T cells, B cells, macrophages, endothelial cells and fibroblasts upon receiving immune stimuli. GM-CSF stimulates stem cells to produce granulocytes and monocytes functions as a cytokine.
• Source: E. coli
• Species: Pig
• Tag: His
• Form: Lyophilized
• Bio-activity: Measure by its ability to induce proliferation in TF-1 cells. The ED50 for this effect is < 3 ng/mL.
• Molecular Mass: The protein has a calculated MW of 15.3 kDa.
  The protein migrates as 17 kDa under reducing condition (SDS-PAGE analysis).
• Protein length: Ala18-Lys144
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Sus scrofa ]
• Official Symbol: CSF2
• Synonyms: CSF2; colony stimulating factor 2 (granulocyte-macrophage); granulocyte-macrophage colony-stimulating factor; CSF; colony-stimulating factor; GM-CSF
• Gene ID: 397208
• mRNA Refseq: NM_214118
• Protein Refseq: NP_999283
• UniProt ID: Q29118

Reviews

01/15/2022

The product's adherence to regulatory standards aligned with our lab's commitment to responsible and transparent research.

07/27/2021

The manufacturer's commitment to meeting regulatory requirements demonstrated its dedication to ethical research practices.

05/19/2019

Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.

Q&As

How conserved is the sequence of CSF2 among different species?

The sequence of CSF2 is moderately conserved across different species.

What is the typical length of CSF2?

The length of CSF2 protein varies but is typically around 144 amino acids.

What is the main biological function of CSF2?

The primary function of CSF2 is to regulate the production and differentiation of white blood cells.

In what tissues or cells is CSF2 commonly expressed?

CSF2 is often expressed in immune cells, specifically in macrophages, T cells, and endothelial cells.

What does CSF2 stand for?

CSF2 stands for Colony Stimulating Factor 2.

Is CSF2 associated with any specific diseases or conditions?

CSF2 dysregulation has been linked to autoimmune diseases and inflammatory disorders.

Which cellular functions are associated with CSF2?

CSF2 is involved in the stimulation of stem cells to produce granulocytes and monocytes.