Active Recombinant Mouse Tnfsf13b Protein

• Cat.No.: Tnfsf13b-6553M
• Product Overview: Purified recombinant protein of Mouse tumor necrosis factor (ligand) superfamily, member 13b (BAFF / Tnfsf13b) without tag was expressed in CHO.

Specification

• Description: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
• Source: CHO
• Species: Mouse
• Bio-activity: The ED50 is 0.5 - 3 ng/mL, corresponding to a specific activity of 0.33 - 2.0 × 10^6 units/mg, determined by the dose dependent stimulation of B cells proliferation.
• Molecular Mass: 22.8 kDa
• Protein length: Ala127-Leu309
• Endotoxin: Less than 1.0 EU/μg protein as determined by the LAL method
• Purity: > 95%, as determined by Coomassie stained SDS-PAGE.
• Stability: Unopened vial can be stored between 2 and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: Protein formulated and vialed at >50 μg/mL in specified buffer
• Storage Buffer: 1 x PBS, pH 6.5

Gene Information

• Gene Name: Tnfsf13b tumor necrosis factor (ligand) superfamily, member 13b [ Mus musculus (house mouse) ]
• Official Symbol: Tnfsf13b
• Synonyms: TNFSF13B; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor ligand superfamily member 13B; B-cell-activating factor; b cell-activating factor; BAFF; BLyS; TALL1; THANK; zTNF4; TALL-1; TNFSF20; D8Ertd387e; MGC124060; MGC124061
• Gene ID: 24099
• mRNA Refseq: NM_033622
• Protein Refseq: NP_296371
• UniProt ID: Q9WU72